PharmD Third Year Notes

Unit I: Pharmacology of anticoagulants, thrombolytics, antiplatelet agents, haemopoietics, and plasma expanders.

Unit II: Pharmacology of diuretics and antidiuretics affecting renal function.

Unit III: Principles of chemotherapy with focus on sulfonamides, co-trimoxazole, penicillins, cephalosporins, tetracyclines, and chloramphenicol.

Unit IV: Pharmacology of macrolides, aminoglycosides, polyene and polypeptide antibiotics, quinolones, fluoroquinolones, antifungal agents, and antivirals.

Unit V: Chemotherapy for tuberculosis, leprosy, malaria, protozoal infections, helminthic diseases, and neoplastic conditions.

Unit VI: Immunopharmacology of immunosuppressants and stimulants, and principles of acute, sub-acute, and chronic animal toxicology.

Unit VII: Structure and function of the cell, chromosome organization, DNA replication, cell cycle regulation, and cell signaling pathways.

Unit VIII: Genome structure and expression, transcription and RNA processing, protein synthesis, genetic alterations, oncogenes, tumor suppressors, gene mapping, gene therapy, and recombinant DNA technology.

Unit I: Principles of quality assurance, validation, calibration, GLP, ISO standards, total quality management, ICH guidelines, and regulatory control in pharmaceuticals.

Unit II: Fundamentals and applications of chromatographic separation techniques including column, TLC, paper, ion-exchange, and partition chromatography.

Unit III: Theory, instrumentation, and applications of HPLC, HPTLC, gas chromatography, electrophoresis, gel filtration, and affinity chromatography.

Unit IV: Principles, instrumentation, and pharmaceutical applications of potentiometry, conductometry, polarography, and amperometric titrations.

Unit V: Theoretical concepts, instrumentation, and pharmaceutical applications of UV-Visible spectroscopy, photometry, and spectrophotometric analysis.

Unit VI: Infrared spectroscopy, fluorimetry, and flame photometry with emphasis on theory, instrumentation, and pharmaceutical applications.

Unit VII: Introduction, theory, and applications of atomic absorption, atomic emission, NMR, ESR, and mass spectrometry.

Unit VIII: Basic principles and applications of polarimetry, X-ray diffraction, and thermal analysis techniques including DSC and DTA.

Unit I: Guidelines for rational antibiotic use and surgical prophylaxis in tuberculosis, meningitis, and respiratory tract infections.

Unit II: Clinical management of gastroenteritis, endocarditis, and septicemia.

Unit III: Diagnosis and treatment of urinary tract infections, malaria, HIV, and opportunistic infections.

Unit IV: Management of fungal, viral, gonococcal, and syphilitic infections.

Unit V: Pharmacotherapy of musculoskeletal disorders including rheumatoid arthritis, osteoarthritis, gout, spondylitis, and systemic lupus erythematosus.

Unit VI: Clinical approaches to acute and chronic renal failure, renal dialysis, and drug-induced renal disorders.

Unit VII: Principles and pharmacotherapy of cancer including breast cancer, leukemia, and management of chemotherapy-induced nausea and emesis.

Unit VIII: Diagnosis and treatment of dermatological conditions including psoriasis, scabies, eczema, and impetigo.

Unit I: Overview of pharmaceutical legislations, principles of professional ethics, and critical analysis of the PCI Code of Pharmaceutical Ethics.

Unit II: Provisions of the Drugs and Cosmetics Act, 1940 and Rules 1945, including legal definitions, relevant schedules, sales, import, labeling, packaging, and regulations for indigenous systems.

Unit III: Constitution and functions of DTAB, DCC, and CDL, along with qualifications, powers, and duties of government analysts and drug inspectors.

Unit IV: Provisions of the Pharmacy Act, 1948 and ER-91, and the Medicinal and Toilet Preparations Act, 1955 including licensing, warehousing, and manufacture of Ayurvedic, Homeopathic, Patent, and Proprietary preparations.

Unit V: Key provisions of the Narcotic Drugs and Psychotropic Substances Act, 1985, its consultative committees, schedules, offences, and penalties, and salient features of the Drugs and Magic Remedies Act.

Unit VI: Essential Commodities Act, 1955 in relation to the Drug Price Control Order and the current National Drug Policy, and the Prevention of Cruelty to Animals Act, 1960.

Unit VII: Provisions of the Patents and Designs Act, 1970 relevant to pharmaceuticals.

Unit VIII: Classification and overview of prescription and non-prescription products.

Unit I: Principles of rational drug design including QSAR, prodrugs, combinatorial chemistry, CADD, antisense molecules, and development of drug classes with SAR, mechanism, synthesis, nomenclature, brands, and side effects.

Unit II: Classification, mechanism, and uses of local anti-infectives, preservatives, antifungal agents, and urinary tract anti-infectives.

Unit III: Pharmacology and chemistry of antitubercular, antiviral, anti-AIDS, antiprotozoal, anthelmintic, antiscabies, and antipedicular agents.

Unit IV: Classification, SAR, synthesis, and uses of sulphonamides, sulphones, and antibiotics.

Unit V: Chemistry, mechanism, and applications of antimalarials and antineoplastic agents.

Unit VI: Pharmacological and chemical aspects of antihypertensives, antianginals, vasodilators, antiarrhythmics, antihyperlipidemics, coagulants, and anticoagulants.

Unit VII: Chemistry and uses of hypoglycemic agents, thyroid and antithyroid agents, and diuretics.

Unit VIII: Properties and applications of diagnostic agents, endocrine and steroidal hormones, and adrenocorticoids.

Unit I: Concept and classification of pharmaceutical dosage forms.

Unit II: Formulation, excipients, granulation, coating, and quality control of various types of tablets.

Unit III: Production, filling, and quality control of hard and soft gelatin capsules.

Unit IV: Formulation, stability, and evaluation of suspensions, emulsions, and solutions.

Unit V: Formulation, containers, sterilization, and quality control of large- and small-volume parenterals.

Unit VI: Classification, preparation, evaluation, and packaging of ophthalmic and topical semi-solid preparations including ointments.

Unit VII: Formulation, preparation, packaging, and evaluation of jellies and suppositories.

Unit VIII: Concepts and examples of controlled and novel drug delivery systems including parenteral, transdermal, buccal, rectal, nasal, implant, and ocular routes.